Pancreas (more of digestion)
Pancreas-secretes 2 classes of things:
Pancreatic bicarbonate: _____________________________________________________________________________________________________________________________________________________________________________________________
exocrine portion secretes a whole host of digestive enzymes-4 major classes of protiolitic enzymes: enzymes that brk down proteins:
1.
2.
3.
4.
These break proteins down to the:
____________________________and_______________________________________
-border brush enzymes break them down to the ______________________________________________necessary to be absorbed across _______________________________________________________________________
-dipeptidases-
1.
2.
3.
2 factors that cause pancreas to secrete these enzymes:
1.
2.
Secretin_________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________
CCK_________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________
-Bacteria is very active here-
1.
2.
3.
-Defecation Reflex
________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________
Break down
-Carbohydrates-
Monosaccharide (glucose), disaccharides (sucrose, lactose, maltose), polysaccharides (3 or more monosaccharide-starch, glycogen, cellulose)
Cellulose________________________________________________________________________________________________________________________________________________________________________________________________________________
Polysaccharides and disaccharides____________________________________________________________________________________________________________________________________________________________________________________________________________
Chemical Breakdown-mouth with salivary amelase(5-10%)-no break down in the stomach-small intestine(pancreatic amelase)breaks down to disaccharide level-border brush enzymes break down to monosaccharide level-absorbed by active transport across duodenal mucosa and early part of jujenum-absorb thru into absorptive cells and into CT lamina propria-pass into portal blood-{drain cap of DS into the cap of liver by hepatic portal vein}-isomers go to liver-liver converts isomers of glucose into glucose-releases it by hepatic vein-into inferior vena cava-to all parts of the body-blood glucose increases-
-insulin is released: 1.
2.
-Lipids-
-triglycerides released into Digestive System (show up as large blobs of fat)
-Bile __________________________________________-pancreatic lipase___________________________________________________ -bile salts form micells-
(Bile salts-one end is hydrophyllic and one end is hydrophobic)
-lipids will pass thru-emulsified fat(micells)-travel to intestinal mucosa-fat will diffuse across cell membrane(fat is nonpolar, membrane is phosolipids)-dissolved into cell-bile salt is left on outside and reabsorbed by the ileum-carried into blood stream back to liver-liver uses it to create more bile
Fat moves across and is reassembled into tryglycerides in intestinal absorptive cell-packaged as lipoproteins for transport (because you can’t put fat into watery substance, so surround it with polar protein coat)-absorbed into lacteal-returned to blood stream at subclavian vein-
1.
2.
Without these: body can’t produce:
Low density-________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________
-contributors:
High density_________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________
-Proteins-
-no breakdown in _________________________________________________
-break down in ___________________________________________________
-acid______________________________________________________
-actual digestion_____________________________________________
Pepsin(10-20%)-break down to poly and dipeptides-small intestine(tripsin, chymatripsin, elastase, carboxypeptidase-break down to dipeptide levels—border brush enzymes break(dipetidases)break down to amino acid level—individual amino acids are actively transported across intestinal mucosa-absorptive cells dump into portal circulation-transport to liver-growth hormone allows movement into cell-
-Water-
-______________________ of water is taken into DS a day
-_______________________is water that we drink
-rest comes from the food we eat
92% water is absorbed ________________________________
6-7%________________________________________________
-converts chyme _________________________________
1-2%-_______________________________________________
-Minerals-
-transported by:
__________________________________________________________________________________________________________________________________________